Entwodiksyon ak aplikasyon de KAS 125995-03-1|Atorvastatin lactone
Atorvastatin lactone se a prodrug for atorvastatin. Li is inhibitor enzyme HMG-CoA redwi, ki enplike in kolestewòl synthesis diminye LDL kolestewòl nivo.
Atorvastatin lactone se absòbe gut nan san yo konvèsyon konvèti atorvastatin, ki gen a pi wo potansyèl atorvastatin lactone. Sa konvèsyon rive fwa cytochrome cytochrome P450 anzime, cytochrome CYP3A4. pharmacokinetics of atorvastatin lactone yo enfliyanse dwòg ke inhibit sa yo enzymes. Atorvastatin ak li yo metabolite yo ekstrè glucuronide glucuronide oswa sulfate konjige.
Atorvastatin intermediate kòm inhibitor of MAP kinase ak/or HMG-CoA redwi tretman nan inflamation.
Sinonims:
5-(4-fluorophenyl){{2}2-[(2R,4R){{6{6}}hydroxy{{7}oxoxan{{8}yl]ethyl]-N,{{10}diphenyl-2-propan{{12{12}}ylpyrrole-3-carboxamide;
Benzeneacetamide,a-cyano{{1}methoxy;
Atorvastatin lactone;
4R)-4-hydroxy{{2}oxo-tetrahydro-pyran-2-yl)-ethyl]{{7{7{7{7{7{7{7{7{7{7{{{{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7{7%}isopropyl-4-phenyl-1H-pyrrole-3-carboxylic asid phenylamide;
CAS 125995-03-1|Atorvastatin lactone
|
ATIK |
ESPESIFIKASYON |
|
KAS |
125995-03-1 |
|
C33H33FN2O4 |
|
|
MW |
540.62 |
|
Bouyi pwen |
674.8±55.0% degre (Prevwa) |
|
Dansite |
1.24±{2{2}.7d.1 g/cm3 (Prevwa) |
|
Fonn pwen |
103-106 degre |
|
solibilite |
Chloroform (Yon ti kras)" 2c DMSO (yon ti kras), Methanol (yon ti kras) |
Presponsab ak transpòtasyon of Entrodiksyon aplikasyon CAS {{0}%%| Atorvastatin lactone
Pake:100g% 2c500g,1kg,25kg,200kg,500kg
Transpòtasyon: pa courier/ pa lè/ pa lanmè
Ki gen rapò Atik of CAS 125995-03-1|Atorvastatin lactone
A roman estrateji nan direksyon atvastatin lactone
P Sawant, ME Maier - Tetrahedron, {1{1}} Elsevier
�% 80� We dekri a roman estrateji atvastatin lactone ki baze sou a Paal–Knorr synthesis of
�% 80� , debenzylation, oxidation ak lakonizasyon atorvastatin lactone 6. kle bilding block, …
Baj popilè: cas:125995-03-1| atorvastatin lactone, Lachin cas:125995-03-1| atorvastatin lactone manifaktirè, faktori
